iMPACT Technology
Preclinical Studies
Key Publications
Dozens of peer-reviewed publications (2016–2025) covering TTF optimization,
electrode arrays, and combination therapies.
  • Effect of Electrode Array Position on Electric Field Intensity in Glioblastoma Patients Undergoing Electric Field Therapy

    Issue Date.April 2025

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  • Optimization of electrode position in electric field treatment for pancreatic cancer

    Issue Date.April 2025

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  • Enhanced anti-tumor effects of combined electric fields, cabozantinib, and radiation therapy in metastatic renal cell carcinoma

    Patent No.March 2025

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  • Feasibility of 3D quality assurance system with electrode array for electric fields therapy

    Patent No.February 2025

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  • Synergistic effects of combined hyperthermia and electric fields treatment in non-small cell lung-cancer (NSCLC) cell lines

    Patent No.October 2024

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  • Correlation between impulse magnitude and inhibition of cell proliferation in alternating electric fields therapy

    Patent No.August 2023

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  • Potential prognostic factor in alternating electric fields therapy based on absorbed energy in tissu

    Patent No.September 2022

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  • Feasibility of a quality assurance system for electromagnetic field therapy

    Patent No.August 2022

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  • Feasibility of a method for optimizing the electrode array structure in tumor-treating fields therapy

    Patent No.August 2022

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  • Technical note: Evaluation of methods for reducing edge current density under electrode arrays for tumor-treating fields therapy

    Patent No.May 2022

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  • The combination of tumor treating fields and hyperthermia has synergistic therapeutic effects in glioblastoma cells by downregulating STAT3

    Patent No.March 2022

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  • Thymidine decreases the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines

    Patent No.May 2021

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  • Tumor treating fields (TTF) treatment enhances radiation-induced apoptosis in pancreatic cancer cells

    Patent No.April 2020

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  • Development of a Method for Improving the Electric Field Distribution in Patients Undergoing Tumor-Treating Fields Therapy

    Patent No.November 2018

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  • Functional Biological Activity of Sorafenib as a Tumor-Treating Field Sensitizer for Glioblastoma Therapy

    Patent No.November 2018

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  • Selective toxicity of tumor treating fields to melanoma: an in vitro and in vivo study

    Patent No.October 2018

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  • Effectiveness of a Fractionated Therapy Scheme in Tumor Treating Fields Therapy

    Patent No.May 2018

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  • Biological effect of an alternating electric field on cell proliferation and synergistic antimitotic effect in combination with ionizing radiation

    Patent No.August 2016

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